Skin Ultrasound as a Diagnostic Approach for Non-melanocytic Benign Skin Tumors
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Keywords

Skin ultrasound
Non-melanocytic benign skin tumor
Diagnosis

DOI

10.36922/itps.v3i2.944

Abstract

Background. The diagnostic imaging techniques in dermatology, such as skin ultrasound, could improve the diagnosis of non-melanocytic benign tumor lesions, especially those of intradermal and subcutaneous nature.

Objective. The general objective of this study was to evaluate the validity and diagnostic safety of high-frequency ultrasound as a diagnostic test for non-melanocytic benign skin tumor detection. The specific objectives were to measure the sensitivity and specificity of ultrasound as a measure of the validity relative to the gold-standard test – diagnostic-therapeutic biopsy.

Methods. This study was carried out between January 2017 and June 2019. The patients (n = 641) included in this study comprised of 318 women and 323 men who were between 48 and 74 years. All of them underwent an ultrasound examination of the skin tumor in the dermatology clinic, the removal of the non-melanocytic tumor, and a final histopathological examination.

Results. The skin ultrasound has a sensitivity and specificity of 93% and 88%, respectively. Furthermore, the positive and negative predictive values of using skin ultrasound are 84% and 94%, respectively.

Conclusion. Skin ultrasound is a diagnostic technique with high sensitivity and specificity in the diagnosis of non-melanocytic skin tumors.

References

Kuwano, Y.; Ishizaki, K.; Watanabe, R.; Nanko, H. Efficacy of Diagnostic Ultrasonography of Lipomas, Epidermalcysts, and Ganglions. Arch. Dermatol., 2009, 145, 761–4.

Jin, W.; Ryu, K.N.; Kim, G.Y.; Kim, H.C.; Lee, J.H.; Park, J.S. Sonographic Findings of Ruptured Epidermal Inclusion Cysts in Superficial Soft Tissue: Emphasison Shapes, Pericystic Changes, and Pericystic Vascularity. J. Ultrasound Med., 2008, 27, 171–6.

Gonzalez, C.P. Characterization of Dermatological Lesions by Ultrasound. Rev. Colomb. Radiol., 2014, 25(3), 4006–14.

Annessi, G.; Bono, R.; Sampogna, F.; Faraggiana, T.; Abeni, D. Sensitivity, Specificity, and Diagnostic Accuracy of Three Dermoscopic Algorithmic Methods in the Diagnosis of Doubtful Melanocytic Lesions: The Importance of Light Brown Structureless Areas in Differentiating Atypical Melanocytic Nevi from thin Melanomas. J. Am. Acad. Dermatol., 2007, 56(5), 759–67.

Pralong, P.; Bathelier, E.; Dalle, S.; Poulalhon, N.; Debarbieux, J. Dermoscopy of Lentigo Malign Melanoma: Report of 125 Cases. Br. J. Dermatol., 2012, 167(2), 280–7

Fonseca, M.; Marchetti, M.A.; Chung, E.; Dusza, S.W.; Burnett, M.E.; Marghoob, A.A.; Geller, A.C.; Bishop, M.; Scope, A.; Halpern, A.C. Cross-sectional Analysis of the Dermoscopic Patterns and Structures of Melanocytic Naevi on the Back and Legs of Adolescents. Br. J. Dermatol., 2015, 173(6), 1486–93.

Alfageme, F. Practical Applications of Ultrasound Skin. Skin, 2012, 27, 204–9.

Minds, O.; Oysul, A.; Harlak, A.; Zeybek, N.; Kozak, O.; Tufan, T. Ultrasonography Accurately Evaluates the Dimension and Shape of the Pilonidal Sinus. Clinics (Sao Paolo), 2009, 64, 189–92.

Wortsman, X.; Worstman, J. Clinical Usefulness of Variable Frequency Ultrasound in Localized Lesions of the Skin. J. Am. Acad. Dermatol., 2010, 62, 247–56.

Wortsman, X. Common Applications of Dermatologic Sonography. J. Ultrasound Med., 2012, 31, 97–111.

R Core Team. A: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria, 2019.

Subirana, I.; Sanz, H.; Vila, J. Building Bivariate Tables: The Compare Groups Package for R. J. Stat. Softw., 2014, 57(12), 1–16.

Hernández, C.; Aguilar, M.; de Troya, M. Ultrasound Applied to the Management of Non-melanoma Skin Cancer. Actas Dermosifiliogr., 2015, 106 Suppl 1, 21–8.

Hernández-Ibáñez, C.; Blazquez-Sánchez, N.; Aguilar-Bernier, M.; Fúnez-Liébana, R.; Rivas-Ruiz, F.; de Troya-Martín, M. Usefulness of Cutaneous Ultrasound in the Classification of Subtypes of Primary Basal Cell Carcinomas. Usefulness of High-Frequency Ultrasound in the Classification of Histologic Subtypes of Primary Basal Cell Carcinoma. Actas Dermosifiliogr., 2017, 108(Suppl 1), 42–51.

Ruiz-Villaverde, R.; Arias-Santiago, S.; Repiso-Jiménez, J.B. Ultrasound in the Management of Benign Cutaneous Tumors. Actas Dermosifiliogr., 2015, 106(Suppl 1), 29–40.

Whittle, C.; Baldassare, G. Ultrasonografia de Piel y Anexos. Rev. Chilena Radiol., 2004, 10(2), 81–88.

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